Insects are attacked by diverse natural enemies, driving the evolution of defence mechanisms. Beyond endogenous defences, many insects recruit symbiont bacteria for protection. This is particularly evident in heritable facultative symbionts, which are common in globally important agricultural and medical pests. However, the dynamics of defensive symbionts in natural insect populations is poorly understood. In particular, it is unclear whether insects recruit different microbes to defend against specific enemies. If true, this would indicate that insect symbionts form a "horizontal gene pool," a reservoir of adaptive traits that insects can exchange to rapidly respond to changing pressures from antagonists.
This project will rigorously test this hypothesis using aphid defensive symbionts as a model system. It builds on pilot data showing that each aphid species typically carries its own ‘parasitoid-specialized’ genotype of the symbiont Hamiltonella defensa that exclusively protects against its primary parasitoid species, the main enemy of aphids. A key unresolve question is how do symbionts resist specific parasitoid species and do aphids share symbionts to defend against common enemies? By employing advanced molecular and experimental techniques, the student will uncover mechanisms of target specificity in defensive symbiont and investigate the ecology of symbiont transmission in insects. Given the presence of defensive symbionts in globally important pests, understanding the factors shaping their microbial communities—and the adaptations they carry—is vital for improving sustainable pest management.
4.大致要求:
We are looking for candidates to have or expecting to receive a first or upper-second class honours degree and a Master’s degree in an area relevant to the project such as agriculture, biology, microbiology, etc.
Knowledge of molecular biology, microbiology, or computational biology is desirable, but not essential.
You must meet the IELTS requirements for your course and upload evidence before CSC’s application deadline, ideally by 1st March 2025. You are therefore strongly advised to sit an approved English Language test as soon as possible, where your IELTS test must still be valid when you enrol for the programme.
5. 语言要求:
https://www.qmul.ac.uk/international-students/englishlanguagerequirements/undergraduate-and-postgraduate-programmes/
选School of Biological and Behavioural Sciences
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