Opening for PhD students at City University of Hong Kong

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We are now having opening for PhD students from a variety of backgrounds (mechanical engineering, chemical engineering, biomedical engineering, chemistry, biology). Candidates with cell culture, nanotechnology, or microfabrication will be highly preferred.



Our lab is focusing on leveraging micro/nanotechnology for investigation of mechanobiology. We have particular interest in cell’s left-right bias, e.g. rightward biased migration, rotation, and orientation. We recently discovered that cells can generate a torque with rotational bias depending on cell types. As a leading group in such rotational mechanics, our research provides a fundamental framework in guiding cell mechanics, stem cell differentiation, and tissue regeneration. Some related publications can be found below:




       
Yuanye Bao, Siying Wu, Lok Ting Chu, Hoi Kwan Kwong, Hogi Hartanto, Yaozhun Huang, Miu Ling Lam, Raymond H. W. Lam & Ting-Hsuan Chen*, Early Committed Clockwise Cell Chirality Up-Regulates Adipogenic Differentiation of Mesenchymal Stem Cells. Advanced Biosystems, vol. 4, pp. 2000161 , 2020
       
Hoi Kwan Kwong, Yaozhun Huang, Yuanye Bao, Miu Ling Lam, Ting-Hsuan Chen*, Remnant Effects of Culture Density on Cell Chirality After Reseeding, ACS Biomaterials Science & Engineering, vol. 5/8, pp. 3944-3953, 2019 (IF: 4.511; rank 8/32 = 25% in Materials Science, Biomaterials)
       
Wei Liu, Yuanye Bao, Miu Ling Lam, Ting Xu, Kai Xie, Hin Sum Man, Edward Y. Chan, Ninghao Zhu, Raymond H. W. Lam, and Ting-Hsuan Chen*, Nanowire Magnetoscope Reveals a Cellular Torque with Left-Right Bias, ACS Nano, vol. 10(8), pp. 7409 - 7417, 2016




In addition, We are also interested in development of biosensors based on nanotechnology and DNA nanomachines. That is to detect biomarkers in live cells or microfluidics assays for portable biosensors. Some related publications can be found below:




       
Siying Wu, Minghui Wu, Gaobo Wang, Ting-Hsuan Chen*, Visual quantitation of silver contamination in fresh water via accumulative length of microparticles in capillary-driven microfluidic devices, Talanta. vol. 235, pp. 122707, 2021 (IF: 6.057, Rank 12/83 14.5% in Chemistry, Analytical, JCR 2020)
       
Gaobo Wang, Lok Ting Chu, Hogi Hartanto, William Budi Utomo, Reynard Aaron Pravasta, Ting-Hsuan Chen*, Microfluidic Particle Dam for Visual and Quantitative Detection of Lead Ions. ACS Sensors. vol. 5, pp. 19 – 23, 2019 (IF: 7.333; rank 3/86 = 3.4% in Chemistry, Analytical, JCR 2019).
       
Zichen Zhao, Yuanye Bao, Lok Ting Chu, John Kin Lim Ho, Ching-Chang Chieng, and Ting-Hsuan Chen*, Microfluidic Bead Trap as a Visual Bar for Quantitative Detection of Oligonucleotides, Lab on a Chip, 2017
       
Shan Chen, Lok Ting Chu, Pak Piu Yeung, Zichen Zhao, Bao Yuanye, Miu Shan Chan, Pik Kwan Lo and Ting-Hsuan Chen*, Enzyme-Free Amplification by Nano-'Sticky Balls' for Visual Detection of ssDNA/RNA Oligonucleotides, ACS Applied Materials & Interfaces, vol. 7(41), pp. 22821-30, 2015




Monthly studentship: HKD 18,527

Regular study period in City U: 4 years



We are open to inquiries regarding the interests of joining our group. If interested, please send you CV and also include the transcripts and English test result (TOEFL, IELTS, or CET-6). The inquiry should be addressed to: thchen@cityu.edu.hk.