The common cold, produced most often by rhinoviruses, is intractable to antiviral defense. A defense against rhinoviruses might nonetheless succeed by exploiting hidden similarities among the rhinovirus strains. For example, most rhinovirus strains bind to the same kind of molecule (delta-receptors) on a cell‘s surface when they attack human cells. Colonno, taking advantage of these common receptors, devised a strategy for blocking the attachment of rhinoviruses to their appropriate receptors. Rather than fruitlessly searching for an antibody that would bind to all rhinoviruses, Colonno realized that an antibody binding to the common receptors of a human cell would prevent rhinoviruses from initiating an infection. Because human cells normally do not develop antibodies to components of their own cells, Colonno injected human cells into mice, which did produce an antibody to the common receptor. In isolated human cells, this antibody proved to be extraordinarily effective at thwarting the rhinovirus. Moreover, when the antibody was given to chimpanzees, it inhibited rhinoviral growth, and in humans it lessened both the severity and duration of cold symptoms.
1. It can be inferred from the passage that a cell
lacking delta-receptors will be
(A) unable to prevent the rhinoviral nucleic acid
from shedding its capsid
(B) defenseless against most strains of rhinovirus
(C) unable to release the viral progeny it develops
after infection
(D) protected from new infections by antibodies
to the rhinovirus
(E) resistant to infection by most strains of
rhinovirus
答案是E,但不明白D项为什么不对?
1.取非题。定位到L6:most rhinovirus strains bind to the same kind of molecule (delta-receptors) on a cell‘s surface when they attack human cells。如果没有molecule (delta-receptors) ,就无法感染,比对答案,选E。D的by后面错了,根据文章可以看出,r感染是通过结合到delta那种表面受体,而没有这种表面受体的话r不会感染,并不是通过一种抗体来使它不感染的。而且这种要取非的题目,找到定位点取非以后多出来的细节就是错的啊!