繁华已谢，梦重新开始，转战SUB

zhangheng1020UID: 2130513

听力圈圈填错8个，差点跳楼~~
还有一套，直接涂到最后多了一个空行出来= =
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add: 刷牙的时候，洗洁精当作牙膏挤在牙刷上了，我当时晕晕乎乎的想，今天牙膏咋没颜色了？

zhangheng1020UID: 2130513

妈的，睡！今天就写了写作文，看了语法，范听。
头疼欲裂！

zhangheng1020UID: 2130513

头疼欲裂睡不着！

zhangheng1020UID: 2130513

爬起来，飘忽中~~

iriszsUID: 210256

看得好心酸

zhangheng1020UID: 2130513

头疼欲裂睡不着！今天3作文，题若干

[ 本帖最后由 zhangheng1020 于 2006-5-10 01:11 编辑 ]

kevin0403UID: 2179200

同样头疼 ~~

你够辛苦的~

zhangheng1020UID: 2130513

爬起，咖啡咖啡咖啡ING~~~
Volume 353:e3  July 21, 2005  Number 3
http://content.nejm.org/cgi/content/full/353/3/e3
Paget's Disease of the Breast
A 70-year-old woman presented with an erythematous, scaly plaque with a hyperpigmented border that had replaced the areola and completely effaced the nipple of the left breast. No breast mass or lymphadenopathy was detected. A skin biopsy demonstrated large round cells, with sizable nuclei and abundant, pale-staining cytoplasm, permeating singly and in groups throughout the epidermis (inset, arrow). Immunohistochemical staining identified carcinoembryonic antigen, confirming the diagnosis of Paget's disease. Mammography and ultrasonography demonstrated no underlying abnormality in the left breast:). A needle-core biopsy of a hypoechoic, ill-defined nodule at the areolar margin of the right breast showed benign, nonproliferative fibrocystic changes without atypia:). The patient declined further treatment and was lost to follow-up. Paget's disease is often associated with underlying in situ or invasive carcinoma of the breast. Careful physical examination for a palpable breast mass or lymphadenopathy is an essential part of the evaluation.

Paget's disease of nipple. Hyperkeratosis of epidermis and chronic inflammation in the dermis are common. Paget's cells permeate through the epidermis.

http://www.breastdiseases.com/slides/ben62.htm
Paget's Disease和Malignant Melanoma咋鉴别涅？

maggie80 wrote:
Paget's disease(PD) of nipple is thought to originate from the glandular epithelial cells underlying dermis, and PD is almost always associated with intraductal carcinoma or invasive carcinoma. So morphologic characteristics and epithelial markers may aid to the diagnosis.
Malignant melanoma arise from melanocyte, the phenotype of IHC is positive for S-100, HMB45, Melan A.

这个Paget's Disease 除了乳房肿瘤还有一个指骨病变的
Paget's disease is characterized by changes in the normal mechanism of bone formation. Bone is a living material made by the body through the continual processes of formation and breakdown (resorption). The combination of these two actions is called remodeling and is used by the body to build bone tissue that is strong and healthy. Strong bones are formed when bone tissue is made up of plateshaped crystals of minerals called hydroxyapatite. Normal wear and tear on the skeletal system is repaired throughout life by the ongoing process of remodeling. In fact, the entire human skeleton is remodeled every five years.
Radiographic Findings
Enlargement of an affected bone, increased opacity of the involved bone, along with a disorganized and coarsened trabecular pattern.


http://www.pathguy.com/~tdemark/0036.htm
Paget's disease of bone.
This is a virus infection of the cells that remodel bone.
You can see the way the bone fibers seem woven, and the bony shelves are divided up by dark cement lines into irregular regions.
This is probably the disease that made Beethoven deaf by compressing his auditory nerves.
[quote]maggie80 wrote:
Actually, Paget's disease means two seperate diseases, but Paget's Disease of the skin is entirely different from Paget's disease of bone.
Particularly, Paget's disease of nipple is pointed out due to its corelation with breast cancer.
These two diseases belong to different entity, just named by the same pathologist James Paget, :)
[url=http://medical-dictionary.thefreedictionary.com/Paget's+disease]Paget's disease[/url]    n.
1. A disease, occurring chiefly in old age, in which the bones become enlarged and weakened, often resulting in fracture or deformation. Also called osteitis deformans.
2. A breast cancer affecting the areola and nipple.
3. A skin cancer arising from apocrine sweat glands.
http://www.answers.com/topic/james-paget
reference
http://www.nature.com/modpathol/ ... /full/3800437a.html
http://courses.washington.edu/hubio553/totrad/SCAR/commonmsk.html

[ 本帖最后由 zhangheng1020 于 2006-5-14 06:13 编辑 ]

kito9695UID: 209685

这两天最主要的是休息好，心态好，不要搞得太疲惫，不利于考场发挥...实力这么久的准备已经积淀好了，临场发挥就愈显重要~!

zhangheng1020UID: 2130513

原帖由 kito9695 于 2006-5-10 07:37 发表
这两天最主要的是休息好，心态好，不要搞得太疲惫，不利于考场发挥...实力这么久的准备已经积淀好了，临场发挥就愈显重要~!

:o放心，我刚才就坐着睡着了，口水一河滩:$
但是我第三遍做题比前两遍错的还多:( 语法5遍了，还是错:L:L

liubai0831UID: 174805

粗略翻了一下这个帖子。

LZ强啊！！！！！

我是学医的，超级理解LZ时间的不充裕。加油吧！！有些申请问题还要向LZ请教。

zhangheng1020UID: 2130513

终于订到房间了~~~ https://bbs.gter.net/viewthre ... &extra=page%3D1
这年头，人都考试考疯了~~

今天没学习，没做题，把张红岩的单词背了3遍

[ 本帖最后由 zhangheng1020 于 2006-5-12 10:28 编辑 ]

zhangheng1020UID: 2130513

生物钟调整的很好

crazylifeUID: 2207778

LZ不上课的？还是在脱产？

zhangheng1020UID: 2130513

郁闷，考完试常规郁闷~~~~ = =
毕竟我已经语法5遍，真题3遍了。作文还是写过的。
目前这个样子，可以说还是没有考好，
现在红宝7遍，蓝宝2遍，黑宝1遍，白宝一边，no阅读做完了，也忘得差不多了。杨鹏难句2遍。填空类比真题作了一点，剩下基本没动。
~~~~~疯料~~~

[ 本帖最后由 zhangheng1020 于 2006-5-14 06:09 编辑 ]